Although various positions adopted during labor and delivery has been studied over thepast 40 years, controversy still surrounds the results regarding obstetric variables. The aim ofthis study was to compare the effect of maternal semi-sitting and dorsal recumbent versuslithotomy positions on the progress of labor. A Quasi-experimental research design wasadopted. Setting: The study was carried out in the labor ward of the General Hospital and theHealth Insurance Hospital in Beni Suef Governorate. The sample were eighty parturientrecruited in each of the three labor positions: semi-sitting (SS), dorsal recumbent (DR), andlithotomy (LI) positions. Tools of data collection were; a structured interview schedule, anassessment sheet of mother fetal condition, and observation checklist: to collect data aboutdetails of second and third stage of labor. The results of the study revealed that the meanduration, frequency, and intensity of the uterine of the contractions were highest in the SSgroup, and lowest in the LI (p<0.001). No significant differences were noticed among thethree groups in their vital signs, but women in the SS group had women who were highermean diastolic pressure (p<0.001). The mean duration of the second and third stages in theSS group was lower than those in the DR and LI groups. Conclusion: The frequency,intensity, and duration of the uterine contractions were better compared to dorsal recumbentand lithotomy positions. The mean durations of the second and third stages were alsosignificantly shorter. Recommendations: the utilization of the semi-sitting labor positionmust be encouraged, with randomized clinical trial to provide further confirmation of thestudy findings.